Always continue the climb. It is possible for you to do whatever you choose, if you first get to know who you are and are willing to work with a power that is greater than ourselves to do it. We are taught you must blame your father, your sisters, your brothers, the school, the teachers - but never blame yourself. Learn from the past, set vivid, detailed goals for the future, and live in the only moment of time.
Learn from the past, set vivid, detailed goals for the future, and live in the only moment of time over which you have any control: now. Optimism is the faith that leads to achievement. Nothing can be done without hope and confidence. If you can dream it, you can do it. Do it now, not tomorrow. Always continue the climb. It is possible for you to do whatever you choose, if you first get to know who you are and are willing to work with a power that is greater than ourselves to do it. We are taught you must blame your father, your sisters, your brothers, the school, the teachers - but never blame yourself
If you first get to know who you are and are willing to work with a power that is greater than ourselves to do it
Learn from the past, set vivid, detailed goals for the future, and live in the only moment of time over which you have any control: now. Optimism is the faith that leads to achievement. Nothing can be done without hope and confidence. If you can dream it, you can do it. Do it now, not tomorrow. Always continue the climb. It is possible for you to do whatever you choose, if you first get to know who you are and are willing to work with a power that is greater than ourselves to do it. We are taught you must blame your father, your sisters, your brothers, the school, the teachers - but never blame yourself
Maisie Lindsay
It is possible for you to do whatever you choose, if you first get to know who you are and are willing to work with a power that is greater than ourselves to do it. We are taught you must blame your father, your sisters, your brothers, the school, the teachers - but never blame yourself.
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Both concourses, the customs facility, baggage declare, and ticketing areas were renovated in late 2017 to mid 2018 below a $4.5 million plan.
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Ruth Jones has admitted that Gavin and Stacey viewers might be left surprised at the Christmas special as she snd
James Corden discussed the final ever episode.
Die-hard fans have been speculating about how the co-creators will round off the show,
with the duo giving an insight on Monday.
Many questions remain unanswered since the last
episode, including what happened after Nessa's shock proposal to Smithy.
While the plot for this year's Christmas special still being kept tightly underwraps, Ruth has revealed that they
are defiantly bring the sitcom to an end.
Speaking in an interview with The Big Issue she said: 'I keep telling people this finale
might not be what you are expecting. And I guarantee we will definitely not be coming back.'
James added: 'What people are going to see on Christmas Day is the culmination of
a 20-year love story, which hopefully shows, if nothing else, that love is complicated and messy
and for everyone.'
Ruth Jones has admitted that Gavin and Stacey viewers might be left surprised at the Christmas special as
she snd James Corden discussed the final ever episode (pictured in March)
Die-hard fans have been speculating about how the co-creators will round off the show, with the duo giving an insight on Monday (James as Smithy,
Mathew Horne as Gavin, Joanna Page as Stacey and Ruth as Nessa)
Elsewhere, one Gavin and Stacey star has confirmed that they will be appearing in the highly-anticipated Christmas special and dropped a major hint about the
final scene.
Steffan Rhodri, known as Dave 'Coaches' Gooch
on the show, has revealed a small spoiler about
the final episode
Speaking to Metro, he said: 'My character Dave is a bit of
an outsider but they planned it so that with the last scene we did,
which is the ending, we were all together and it was very touching.'
He added that he can't say anything else about the Christmas special, but he
can confirm that he will be in it.
Steffan missed the 2019 Christmas special, meaning he hasn't filmed for the show in 17 years.
He said: 'I actually enjoyed it more than I thought I would. It
was like putting on a pair of old trousers. It was
really lovely to hang out with them again.'
Fans know coach driver Dave for his iconic line about what he will and wont put
up with on his coach - 'fags and weed, glue and speed, but I draws the line at crack'.
But what they may not know is that Steffan based the character on his uncle who is a coach
driver with a similar attitude.
Many questions remain unanswered since the last episode, including what happened after Nessa's shock proposal to Smithy
Speaking in an interview with The Big Issue Ruth said: 'I keep telling people this finale might not be what you are
expecting. And I guarantee we will definitely not be coming back'
Steffan Rhodri, known as Dave 'Coaches' Gooch on the show, has revealed a small spoiler about the final episode
earlier this week, revealing that he will feature
'When he realised I'd based Dave on him he was quite chuffed,'
the actor said.
Many questions remain unanswered about the final episode, including
what really happened on that fishing trip with Dave,
Bryan and Jason.
Cast members have been spotted on set filming scenes but have kept filming details
a secret.
It has been reported that the cast and crew have been told to hide
their scripts and to be on 'high alert' when it comes to leaks.
The Gavin and Stacey Christmas Special airs at Christmas
Day at 9pm on BBC One and BBC iPlayer.
James Corden
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PMI's U.S. launch of flagship IQOS device needs FDA green light
*
Six health campaign groups wrote letter to FDA criticising PMI
Say PMI misrepresented past FDA decisions on IQOS
*
PMI says it discusses its products in accordance with law
*
FDA acknowledges receiving campaigners' letter
By Emma Rumney
LONDON, July 16 (Reuters) - Health campaigners have
written to U.S. regulators accusing Philip Morris International
of misrepresenting past regulatory decisions, seeking to
disrupt the launch of its flagship heated tobacco device IQOS in the United States.
The world's biggest tobacco company by market value has spent billions
of dollars developing the product, which investors see as key
to driving future growth. But it needs permission from the U.S.
Food and Drug Administration to sell it in the world's second largest tobacco market by revenue.
Six anti-tobacco and health groups, including the
Campaign for Tobacco-Free Kids, the American Academy of Pediatrics and the American Lung Association, wrote to the FDA to oppose IQOS-related applications PMI
has submitted to the agency.
"PMI has repeatedly made misleading and deceptive statements wrongly suggesting that the FDA has found that IQOS reduces the risk of disease," the letter,
dated June 27 and reviewed by Reuters, said.
The campaign groups allege that PMI violated the FDA's orders by suggesting IQOS offered lower
risks than cigarettes. Their letter cited four examples of such
statements in the United States, the Philippines, Mexico and Kazakhstan.
They also said in the letter that upcoming independent studies contradict PMI's findings about how many IQOS users
completely switch to the device from cigarettes.
Presentations on the studies from the International Tobacco Control
Project (ITC) at Canada's University of Waterloo are attached to the letter as exhibits.
They show the ITC found a far lower rate of IQOS users had quit
smoking in Japan and Korea than estimates from PMI.
These factors "directly bear on whether PMI should be permitted to market IQOS" in the United States, the campaigners'
letter said.
The contents of the letter have not been previously reported.
Asked by Reuters to respond to the letter,
a PMI spokesperson said the company was proud
to discuss the FDA's conclusions on IQOS.
The spokesperson did not address each example but said some of the language flagged by campaigners was,
in the company's view, compatible with the FDA's orders.
"Wherever we discuss our science and our products, we do so in accordance with all applicable laws,"
the spokesperson said.
Reuters could not determine whether the campaigners' letter would change the FDA's approach to IQOS.
The agency said it had received the letter and
would respond directly to the senders. It did not comment further.
Devices like IQOS heat up sticks of ground tobacco without burning
them in an attempt to avoid the harmful chemicals released via
combustion.
The FDA first authorised PMI to sell an older version of IQOS in 2019.
It subsequently authorised the company to
market it as offering reduced exposure to harmful chemicals
versus cigarettes for smokers who completely switch - known as an "exposure modification order".
The FDA can also issue a "risk modification order", authorising
a company to claim its product reduces the risk of tobacco-related harm and
disease. But this is harder to prove, especially without
long-term, epidemiological studies.
The FDA rejected PMI's previous application to say its older IQOS device results in reduced health risks, saying there wasn't sufficient
evidence to support this.
PMI applied in 2023 to renew its existing exposure modification orders.
Later that year, it also applied to sell and market a newer
version of the IQOS device in the same way.
The FDA has yet to decide on these applications.
Marketing the product as having health benefits
compared to traditional cigarettes could help PMI
persuade consumers to switch as well as afford
it tax benefits versus cigarettes in some U.S. states.
SWITCH RATES
The campaign groups also cited preliminary data from ITC studies in Japan and Korea, saying it contradicted PMI's findings about how
many IQOS users completely switch from cigarettes.
The studies have been presented at academic conferences but have not yet
been submitted for publication in a journal, ITC researchers told Reuters.
As a result, study abstracts have been peer reviewed but the full findings
have yet to go through that process.
Japan is IQOS' largest market and the introduction of heated tobacco there coincided with an accelerated decline in cigarette sales.
PMI estimates more than seven out of 10 of its registered IQOS customers
globally have quit cigarettes. A 2023 PMI application to the FDA emphasised that the majority of IQOS users were
using IQOS exclusively.
However, the ITC's researchers put the percentage of
all IQOS users that had quit smoking at just 15% in Japan and 30% in Korea in 2021.
Users most commonly used IQOS and cigarettes simultaneously, known as "dual use", often leading to an overall
increase in tobacco consumption, the ITC researchers found.
PMI pointed to a 2019 Japanese government health survey, where 75% of respondents
who reported using heated tobacco said they
did not smoke.
However, a paper published this year, led by researchers
from Georgetown University, highlighted flaws in the government's survey, including changes to
the question format that can lead to under-reporting
of smoking.
Other surveys have also found higher rates of dual use than the government, it said.
(Reporting by Emma Rumney; Editing by Matt Scuffham and Emelia Sithole-Matarise)
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